Colon cancer deaths are moving briskly down across the U.S. — with the exception of three large hotspots, researchers reported Wednesday.

A "perfect storm" of high obesity rates, low education and a lack of access to medical care make for frighteningly high colon cancer rates in the Mississippi delta, western Appalachia and the borderland between Virginia and North Carolina, the American Cancer Society finds. 

"In the Mississippi delta, rates among black men are not declining at all," said Rebecca Siegel of the

American Cancer Society, who led the study.
Colon cancer has become one of the most easily prevented cancers. Colonoscopy can spot and remove pre-cancerous growths before they become malignant, or find tumors early, when they are still easy to treat. Surgery can remove colon cancers, and there are several good chemotherapy drugs that can control it.
"It really is like a perfect storm."
And the 2010 Affordable Care Act means that health insurers must pay for colon cancer screening. But that only works if people actually have health insurance, and that's a challenge on some of these areas, Siegel said. 

"Particularly in the lower Mississippi delta and Appalachia, there are longstanding challenges, with high poverty, unemployment which coincides with less insurance coverage," she told NBC News.
A diet that's rich in fat, sugar and red meat and low in fiber doesn't help.
These three regions are 'hotspots' for colon cancer deaths, a new study finds. Graphic Courtesy of the American Cancer Society
"It really is like a perfect storm," Siegel said.

Politics may be interfering, too. The Affordable Care Act, widely known as Obamacare, helps subsidize health insurance for low-income people. But it also relies on states expanding Medicaid, the joint state-federal health insurance plan for the poor. "Only half of the 12 states that are involved in these high-risk areas have expanded Medicaid," Siegel said. 

That means many people whose incomes are too low to qualify for subsidized insurance are left with very few options for paying for health care.